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Product Information
Description |
TRAF4 rabbit polyclonal |
Protein full name |
TNF receptor-associated factor 4 |
Synonyms |
Cysteine-rich motif associated to RING and Traf domains protein 1, Traf4, Cart1, MLN62, tumor necrosis receptor-associated factor 4A |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human TRAF4 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Nucleus, Cytoplasm |
Predicted MW. |
53 kDa |
Observed MW. |
53 kDa |
Uniprot ID |
Q9BUZ4, Q61382, A8DYU9 |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
thymus, brain, lymph nodes |
IHC |
Mouse, Rat |
1: 250-1: 500 |
lymphoid, thymus |
IF |
Mouse, Rat |
1: 150-1: 300 |
lymphoid, thymus |
Background
The tumor necrosis factor receptor-associated factor (TRAF) family is a group of signaling adaptors which participate in various signaling pathways through binding of the tumor necrosis factor receptor super family. As one of the important member of TRAF family proteins, TRAF4 was initially isolated from breast carcinomas and identified as the first member of the TRAF family to be up-regulated in human carcinomas. TRAF4 is required during embryo genesis in key biological processes including the formation of the trachea, the development of the axial skeleton, and the closure of the neural tube. TRAF4 deficiency leads to severe developmental alterations.
Images
|
Western blot analysis of TRAF4 (GB111015) at dilution of 1: 1000 Lane 1: Hela cell lysate Lane 2: Jurkat cell lysate Lane 3: THP-1 cell lysate Lane 4: Mouse thymus tissue lysate Lane 5: Mouse brain tissue lysate Lane 6: Mouse lymph nodes tissue lysate Lane 7: Rat thymus tissue lysate Lane 8: Rat brain tissue lysate Lane 9: Rat lymph nodes tissue lysate |
|
Immunohistochemistry analysis of paraffin-embedded mouse lymphoid using TRAF4 (GB111015) at dilution of 1: 250 |
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Immunohistochemistry analysis of paraffin-embedded rat thymus using TRAF4 (GB111015) at dilution of 1: 250 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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