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Anti -L1CAM Rabbit pAb

價格: 在線咨詢
貨號:
KT012238
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
MR
購買數(shù)量:
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Product Information


Description

L1CAM rabbit polyclonal antibody

Protein full name

Neural cell adhesion molecule L1

Synonyms

NCAM-L1, CD171, L1cam, Caml1, L1-NCAM, HSAS, Hyd

Immunogen

Recombinant protein corresponding to Human L1CAM

Isotype

IgG

Purity

Affinity purification

Predicted MW.

141 kDa

Observed MW.

220 kDa

Uniprot ID

P11627, Q05695




Applications


Applications

Species

Dilution

Positive Sample

WB

Mouse, Rat

1: 500-1: 1000

brain, cerebellum, cerebral cortex




Background

L1cam (L1 cell adhesion molecule isoform 1 precursor) is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.




Images


Picture 1.png

Western blot analysis of CD171 (GB111218) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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