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Product Information
Description |
N Cadherin rabbit polyclonal antibody |
Protein full name |
Cadherin-2 |
Synonyms |
Neural cadherin, N-cadherin, CD325, CDw325, Cadherin 2 N cadherin neuronal, CDHN, Cdh2, Cadherin 2 type 1, NCAD, N cadherin 1 |
Immunogen |
Recombinant protein corresponding to Mouse N Cadherin |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Cell membrane |
Predicted MW. |
100 kDa |
Observed MW. |
140 kDa |
Uniprot ID |
P19022, P15116, Q9Z1Y3 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
WB |
Human, Mouse, Rat |
1:500-1:1000 |
heart, brain, testis |
IHC/IF |
Mouse, Rat |
1:1500-1:3000 |
heart, testis |
Background
This gene is a classical cadherin from the cadherin super family. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.
Images
|
Western blot analysis of N-Cadherin (GB111273) at dilution of 1: 500 |
|
Immunohistochemistry of paraffin embedded mouse heart using N-Cadherin (GB111273) at dilution of 1: 1500 (200x lens) |
|
Immunohistochemistry of paraffin embedded rat heart using N-Cadherin (GB111273) at dilution of 1: 1500 (200x lens) |
|
Immunofluorescence of paraffin embedded rat testis using N-Cadherin (GB111273) at dilution of 1: 1500 (200x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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