Anti -beta Catenin Mouse mAb

價格：在線咨詢

貨號：

DRF101295

產(chǎn)品規(guī)格：

100 μL850

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	beta Catenin mouse monoclonal
Protein full name	Catenin beta-1
Synonyms	CTNNB1, CTNNB, MRD19, armadillo, catenin beta 1
Immunogen	Recombinant protein corresponding to Mouse β-catenin
Isotype	IgG
Predicted MW.	92 kDa
Observed MW.	92 kDa
Purity	Affinity purification
Subcellular location	Cytoplasm, Nucleus, Cell junction, Cell membrane
Uniprot ID	P35222, Q02248, Q9WU82

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1: 500-1: 1000	lung, kidney
IHC	Human, Mouse, Rat	1: 100-1: 500	stomach, colon
IF	Human, Mouse, Rat	1: 100-1: 500	stomach, colon

Background

β-catenin is a dual function protein, involved in regulation and coordination of cell–cell adhesion and gene transcription. In humans, the CTNNB1 protein is encoded by the CTNNB1 gene. In Drosophila, the homologous protein is called armadillo. β-catenin is a subunit of the cadherin protein complex and acts as an intracellular signal transducer in the Wnt signaling pathway. It is a member of the catenin protein family and homologous to γ-catenin, also known as plakoglobin. Beta-catenin is widely expressed in many tissues. In cardiac muscle, beta-catenin localizes to adherens junctions in intercalated disc structures, which are critical for electrical and mechanical coupling between adjacent cardiomyocytes.

Images

	Western blot analysis of β-catenin (GB12015) at dilution of 1: 1000. Lane 1: Mouse lung tissue lysate Lane 2: Mouse kidney tissue lysate Lane 3: Rat kidney tissue lysate
	Immunohistochemistry analysis of paraffin-embedded mouse stomach using β-catenin (GB12015)at dilution of 1: 200
	Immunohistochemistry analysis of paraffin-embedded rat stomach using β-catenin (GB12015)at dilution of 1: 200
	Immunohistochemistry analysis of paraffin-embedded rat colon using β-catenin (GB12015)at dilution of 1: 200

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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