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Product Information
Description |
CD133 mouse monoclonal |
Protein full name |
Prominin-1 |
Synonyms |
PROM1, AC133, CD133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4, prominin 1 |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse CD133 |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location |
Apical cell membrane,Cell projection,Endoplasmic reticulum |
Uniprot ID | O54990 |
Applications
Applications | IHC,IF |
Species | Rat |
Dilution | 1:200-1:800 |
Positive tissue | Fetal rat tissue |
Background
May play a role in cell differentiation, proliferation and apoptosis . Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.
Images
Immunohistochemistry analysis of paraffin-embedded fetal rat using CD133 (GB12060) at dilution of 1:400 |
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Immunohistochemistry analysis of paraffin-embedded fetal rat using CD133 (GB12060) at dilution of 1:400 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.
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