Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol.
Images
Western blot analysis of Cytochrome c (GB12080) at dilution of 1: 1000 .
Lane 1: Mouse heart tissue lysate
Lane 2: Mouse heart tissue lysate
Lane 3: Rat heart tissue lysate
Lane 4: Rat heart tissue lysate
Immunohistochemistry analysis of paraffin-embedded human stomach using Cytochrome c (GB12080) at dilution of 1: 1000
Immunofluorescence analysis of paraffin-embedded rat heart using Cytochrome c (GB12080) at dilution of 1: 1000
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .