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Product Information
Description |
c-Fos mouse monoclonal |
Protein full name |
Proto-oncogene c-Fos |
Synonyms |
FOS, AP-1, C-p55, Fos proto-oncogene, AP-1 transcription factor subunit |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human c-Fos |
Isotype |
IgG |
Predicted MW. |
62 kDa |
Observed MW. |
62 kDa |
Purity |
Affinity purification |
Subcellular location |
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Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse |
1: 500-1: 2000 |
lung, brain, kidney |
IHC |
Human, Mouse, Rat |
1: 500-1: 2000 |
brain |
IF |
Human, Mouse, Rat |
1: 200-1: 1000 |
brain |
Background
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Images
Western blot analysis of c-Fos (GB12069) at dilution of 1: 1000 |
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Western blot analysis of c-Fos (GB12069) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse brain using c-Fos (GB12069) at dilution of 1: 2000 |
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Immunohistochemistry analysis of paraffin-embedded rat brain using c-Fos (GB12069) at dilution of 1: 2000 |
Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using c-Fos (GB12069) at dilution of 1: 2000 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat brain using c-Fos (GB12069) at dilution of 1: 2000
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Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.
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