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Product Information
Description |
E Cadherin mouse monoclonal |
Protein full name |
Cadherin-1 |
Synonyms |
CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO, cadherin 1, BCDS1, E-Cadherin, CAM 120/80, Epithelial cadherin |
Immunogen |
Human recombinant E-Cadherin protein expressed in MCF7 cells |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Cell membrane, Cytoplasm |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Human, Mouse, Rat |
1: 500-1: 1000 |
colon cancer, stomach cancer, liver, colon, stomach, small intestine |
Background
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.
Images
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Immunohistochemistry analysis of paraffin-embedded human colon cancer using E Cadherin (GB12083) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse stomach cancer using E Cadherin (GB12083) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse liver using E Cadherin (GB12083) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse liver using E Cadherin (GB12083) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse colon using E Cadherin (GB12083) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse stomach using E Cadherin (GB12083) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat small intestine using E Cadherin (GB12083) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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