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Anti -EGFR Mouse mAb

價(jià)格: 在線咨詢
貨號:
DRF101312
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

EGFR mouse monoclonal

Protein full name

Epidermal growth factor receptor

Synonyms

EGFR, ERBB, ERBB1, HER1, NISBD2, PIG61, mENA, epidermal growth factor receptor

Immunogen

KLH conjugated Synthetic peptide

corresponding to Human EGFR

Isotype

IgG

Subcellular location

Cytoplasm, Nucleus, Cell membrane, Secreted

Predicted MW.

134 kDa

Observed MW.

175 kDa

Purity

Affinity purification

Uniprot ID

P00533



Applications


applications species dilution Positive tissue
WB Human 1: 500-1: 1000 A549, HepG2, A431




Background

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.




Images


Western blot analysis of EGFR (GB12084)
at dilution of 1: 1000
Lane 1: A549 cell lysate
Lane 2: HepG2 cell lysate
Lane 3: A431 cell lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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