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Product Information
Description |
EGFR mouse monoclonal |
Protein full name |
Epidermal growth factor receptor |
Synonyms |
EGFR, ERBB, ERBB1, HER1, NISBD2, PIG61, mENA, epidermal growth factor receptor |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human EGFR |
Isotype |
IgG |
Subcellular location |
Cytoplasm, Nucleus, Cell membrane, Secreted |
Predicted MW. |
134 kDa |
Observed MW. |
175 kDa |
Purity |
Affinity purification |
Uniprot ID |
Applications
applications | species | dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | A549, HepG2, A431 |
Background
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Images
Western blot analysis of EGFR (GB12084) at dilution of 1: 1000 Lane 1: A549 cell lysate Lane 2: HepG2 cell lysate Lane 3: A431 cell lysate |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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