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Anti -ERK1+ ERK2 Mouse mAb

價(jià)格: 在線咨詢
貨號:
DRF101315
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

ERK1+ ERK2 mouse monoclonal

Protein full name

Mitogen-activated protein kinase 3/

Mitogen-activated protein kinase 1

Synonyms

MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK, mitogen-activated protein kinase 3; MAPK1, ERK, ERK-2, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk, p42-MAPK

Immunogem

Recombinant protein corresponding to Mouse ERK1+ERK2

Isotype

IgG

Predicted MW.

43 kDa

Observed MW.

43 kDa

Purity

Affinity purification

Uniprot ID

P27361, P21708, Q63844,

P28482, P63086, P63085



Applications


Applications

Species

Dilution

Postive Tissue

WB

Human, Rat, Mouse

1: 500-1: 1000

lung, kidney, brain



Background


Mitogen-activated protein kinase 3 is an enzyme that in humans is encoded by the MAPK3 gene. The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Pharmacological inhibition of ERK1/2 restores GSK3β activity and protein synthesis levels in a model of tuberous sclerosis.




Images



圖片 1.png

Western blot analysis of ERK1+ ERK2 (GB12087) at dilution of 1: 1000




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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