Anti -GFAP Mouse mAb

價(jià)格：在線咨詢

貨號(hào)：

DRF101319

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬(wàn)物

購(gòu)買數(shù)量：

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產(chǎn)品詳情操作說(shuō)明注意事項(xiàng)

Product Information

Description	GFAP mouse monoclonal
Protein full name	Glial fibrillary acidic protein
Synonyms	GFAP, ALXDRD, glial fibrillary acidic protein
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse GFAP
Isotype	IgG
Predicted MW.	49KDa
Observed MW.	49KDa
Purity	Affinity purification
Subcellular location	Cytoplasm
Uniprot ID	P03995,P47819

Applications

applications	species	dilution	Positive tissue
WB	Mouse,Rat	1:500-1:5000	brain, cerebral cortex, spinal cord
IHC	Mouse,Rat	1:500-1:2000	brain
IF	Mouse,Rat	1:500-1:2000	brain

Background

Glial fibrillary acidic protein is an intermediate filament (IF) protein that is expressed by numerous cell types of the central nervous system (CNS) including astrocytes and ependymal cells.GFAP has also been found to be expressed in glomeruli and peritubular fibroblasts taken from rat kidneys Leydig cells of the testis in both hamsters and humans, human keratinocytes, human osteocytes and chondrocytes and stellate cells of the pancreas and liver in rats. It is closely related to its non-epithelial family members, vimentin,desmin, and peripherin, which are all involved in the structure and function of the cell’s cytoskeleton.

Images

	Western blot analysis of GFAP (GB12096) at dilution of 1:1000
	Immunohistochemistry analysis of paraffin-embedded mouse brain using GFAP (GB12096) at dilution of 1:1200
	Immunohistochemistry analysis of paraffin-embedded rat brain using GFAP (GB12096) at dilution of 1:1200
	Immunofluorescence analysis of paraffin-embedded mouse brain using GFAP (GB12096) at dilution of 1:1000
	Immunofluorescence analysis of paraffin-embedded rat brain using GFAP (GB12096) at dilution of 1:1000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

Publications:

	Title	Journal	Pubmed ID	Application
1	Knockdown of T Cell Immunoglobulin and Mucin 1 (Tim-1) Suppresses Glioma Progression Through Inhibition of the Cytokine-PI3K/AKT Pathway.	OncoTargets and therapy	32801766	IF
2	Activation of PPAR-β/δ Attenuates Brain Injury by Suppressing Inflammation and Apoptosis in a Collagenase-Induced Intracerebral Hemorrhage Mouse Model.	Neurochemical Research	31939088	IF
3	LY354740 Reduces Extracellular Glutamate Concentration, Inhibits Phosphorylation of Fyn/NMDARs, and Expression of PLK2/pS129 α-Synuclein in Mice Treated With Acute or Sub-Acute MPTP.	Frontiers in Pharmacology	32180729	IF
4	Differences in neurotropism and neurotoxicity among retrograde viral tracers.	Molecular Neurodegeneration	30736827	IF
5	Cdc42-Dependent Transfer of mir301 from Breast Cancer-Derived Extracellular Vesicles Regulates the Matrix Modulating Ability of Astrocytes at the Blood-Brain Barrier.	International Journal of Molecular Sciences	32481745
6	Fushiming Capsule Attenuates Diabetic Rat Retina Damage via Antioxidation and Anti-Inflammation.	Evidence-based Complementary and Alternative Medicine : Ecam	31396288

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