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Anti -Nucleophosmin Mouse mAb
價格：
在線咨詢
貨號：
DRF101325
產(chǎn)品規(guī)格：
100 μL
Applications：
Species：
購買數(shù)量：
產(chǎn)品詳情
操作說明
注意事項
Product Information
|
Description |
Nucleophosmin mouse monoclonal |
|
Protein full name |
Nucleophosmin |
|
Synonyms |
NPM, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Numatrin, Npm1 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Nucleophosmin |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
|
|
Predicted MW. |
33 kDa |
|
Observed MW. |
40 kDa |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
spleen, testis |
Background
Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF.
Acts as a chaperonin for the core histones H3, H2B and H4. Stimulates APEX1endonuclease activity on apurinic/apyrimidinic double-stranded DNA but inhibits APEX1 endonuclease activity on AP single-stranded RNA. May exert a control of APEX1 endonuclease activity within nucleoli devoted to repair AP on rDNA and the removal of oxidized rRNA molecules. In concert with BRCA2, regulates centrosome duplication.
Images
|
Western blot analysis of Nucleophosmin (GB121043) at dilution of 1: 1000 Lane 1: Hela cell lysate Lane 2: HepG2 cell lysate Lane 3: MCF7 cell lysate Lane 4: NIH3T3 cell lysate Lane 5: PC12 cell lysate Lane 6: Mouse spleen tissue lysate Lane 7: Mouse testis tissue lysate Lane 8: Rat spleen tissue lysate Lane 9: Rat testis tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號合肥國家大學(xué)科技園A401室