Anti -Iba1 Mouse mAb

價格：在線咨詢

貨號：

DRF101326

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	Iba1 mouse monoclonal
Protein full name	Allograft inflammatory factor 1
Synonyms	AIF1, AIF-1, IBA, IRT-1, IRT1, allograft inflammatory factor 1
Immunogen	Recombinant protein corresponding to Mouse Iba1
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoskeleton, Plasma membrane
Uniprot ID	O70200, P55009

Applications

applications	species	dilution	Positive tissue
IHC	Mouse, Rat	1: 500-1: 1000	brain
IF	Mouse, Rat	1: 500-1: 1000	brain, hippocampus

Background

Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

Images

	Immunohistochemistry analysis of paraffin-embedded mouse brain using Iba1 (GB12105) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded rat brain using Iba1 (GB12105) at dilution of 1: 1000
	Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using Iba1 (GB12105) at dilution of 1: 1000
	Immunofluorescent analysis of paraformaldehyde-fixed rat brain using Iba1 (GB12105) at dilution of 1: 1000
	Immunofluorescent analysis of paraformaldehyde-fixed rat hippocampus using Neun (GB11138) (green) + Iba1 (GB12105) (red) + MBP (GB12226) (spred) + GFAP (GB11096) (yellow) and Dapi in blue at dilution of 1: 1000
	Immunofluorescent analysis of paraformaldehyde-fixed rat brain using Neun (GB11138) (green)+ Iba1 (GB12105) (spred) + MAP2 (GB11128-2) (red) and Dapi in blue at dilution of 1: 1000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

Publications:

	Title	Journal	Pubmed ID	Application
1	Sodium para-aminosalicylic acid inhibits manganese-induced NLRP3 inflammasome-dependent pyroptosis by inhibiting NF-κB pathway activation and oxidative stress.	Journal of Neuroinflammation	33203418	IF
2	Light Emitting Diode Therapy Protects against Myocardial Ischemia/Reperfusion Injury through Mitigating Neuroinflammation.	Oxidative Medicine and Cellular Longevity	32963707	IF
3	Hydrogen Sulfide Reduces Cognitive Impairment in Rats After Subarachnoid Hemorrhage by Ameliorating Neuroinflammation Mediated by the TLR4/NF-κB Pathway in Microglia.	Frontiers in Cellular Neuroscience	32754015	IF
4	Activation of PPAR-β/δ Attenuates Brain Injury by Suppressing Inflammation and Apoptosis in a Collagenase-Induced Intracerebral Hemorrhage Mouse Model.	Neurochemical Research	31939088	IF
5	Clemastine improves hypomyelination in rats with hypoxic-ischemic brain injury by reducing microglia-derived IL-1β via P38 signaling pathway.	Journal of Neuroinflammation	32061255	IF
6	Light-emitting diode therapy protects against ventricular arrhythmias by neuro-immune modulation in myocardial ischemia and reperfusion rat model.	Journal of Neuroinflammation	31287006	IF

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