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Product Information
Description |
Amyloid beta 40 mouse monoclonal |
Protein full name |
Amyloid beta A4 protein |
Synonyms |
ABPP, APP, N-APP, Soluble APP-alpha, |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Amyloid beta 40 |
Isotype |
IgG1 |
Purity |
Affinity purification |
Subcellular location |
Cell Membrane, Cytoplasm, Nucleus, Secreted |
Uniprot ID |
P12023 |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Mouse |
1: 1200-1: 2400 |
brain |
Background
Most of autosomal dominant familial AD can be attributed to mutations in one of three genes: those encoding amyloid precursor protein (APP) and presenilins 1 and 2 Most mutations in the APP and presenilin genes increase the production of a small protein called Aβ42, which is the main component of senile plaques. Some of the mutations merely alter the ratio between Aβ42 and the other major forms—particularly Aβ40—without increasing Aβ42 levels.
Images
Immunohistochemistry analysis of paraffin-embedded mouse brain using Aβ40 (GB121197) at dilution of 1: 2400 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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