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Anti -Amyloid beta 40 Mouse mAb

價格: 在線咨詢
貨號:
DRF101340
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
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Product Information


Description

Amyloid beta 40 mouse monoclonal

Protein full name

Amyloid beta A4 protein

Synonyms

ABPP, APP, N-APP, Soluble APP-alpha,
S-APP-alpha, C99, APP-C99, Abeta42, Abeta40, Beta-APP40, C83, APP-C59, Amyloid intracellular domain 59, APP-C57, Gamma-CTF(50), C31, App, Aβ40, Aβ42, A beta 40,beta Amyloid 40

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse Amyloid beta 40

Isotype

IgG1

Purity

Affinity purification

Subcellular location

Cell Membrane, Cytoplasm, 

Nucleus, Secreted

Uniprot ID

P12023




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse

1: 1200-1: 2400

brain




Background


Most of autosomal dominant familial AD can be attributed to mutations in one of three genes: those encoding amyloid precursor protein (APP) and presenilins 1 and 2 Most mutations in the APP and presenilin genes increase the production of a small protein called Aβ42, which is the main component of senile plaques. Some of the mutations merely alter the ratio between Aβ42 and the other major forms—particularly Aβ40—without increasing Aβ42 levels.




Images


圖片 1.png

Immunohistochemistry analysis of paraffin-embedded mouse brain using 

Aβ40 (GB121197) at dilution of 1: 2400




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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