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Anti -ROR alpha/RORA Mouse mAb

價(jià)格: 在線(xiàn)咨詢(xún)
貨號(hào):
DRF101347
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購(gòu)買(mǎi)數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

ROR alpha/RORA mouse monoclonal

Protein full name

Nuclear receptor ROR-alpha

Synonyms

Nuclear receptor RZR-alpha, Nuclear receptor subfamily 1 group F member 1, RAR-related orphan receptor A, Retinoid-related orphan receptor-alpha, Rora, Nr1f1, Rzra

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse ROR alpha/RORA

Isotype

IgG2a

Purity

Affinity purification

Subcellular location

Nucleus

Uniprot ID

P35398, P51448




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Human, Mouse, Rat

1: 1000-1: 2000

kidney cancer, brain, heart




Background


RORA is a steroid hormone receptor and has been implicated in the pathology of circadian rhythms, bone growth, angiogenesis, development of cones, cellular metabolism and a mediator in the immune and lipid metabolism pathways . It binds DNA as a monomer to hormone response elements (HRE) containing a single core motif half-site preceded by a short A-T-rich sequence, which binds to the consensus sequence 5'-[AT][TA]A[AT][CGT]TAGGTCA-3'. Regulates a number of genes involved in lipid metabolism such as apolipoproteins AI, APOA5, CIII, CYP71 and PPARgamma, in cerebellum and photoreceptor development including PCP2, OPN1SW, OPN1SM AND ARR3, in circadian rhythm with BMAL1, and skeletal muscle development with MYOD1 .




Images


Immunohistochemistry analysis of paraffin-embedded human kidney cancer  using RORA (GB121300) at dilution of 1: 2000

Immunohistochemistry analysis of paraffin-embedded mouse brain using 

RORA (GB121300) at dilution of 1: 2000

Immunohistochemistry analysis of paraffin-embedded rat brain using 

RORA (GB121300) at dilution of 1: 2000


Immunohistochemistry analysis of paraffin-embedded mouse heart using 

RORA (GB121300) at dilution of 1: 2000

Immunohistochemistry analysis of paraffin-embedded rat heart using 

RORA (GB121300) at dilution of 1: 2000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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