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Anti -N Cadherin Mouse mAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101352
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

N Cadherin mouse monoclonal

Protein full name

Cadherin-2

Synonyms

Neural cadherin, N-cadherin, CD325, CDw325,

Cadherin 2 N cadherin neuronal, CDHN, Cdh2,

Cadherin 2 type 1, NCAD, N cadherin 1

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse N-cadherin

Isotype

IgG

Subcellular location

Membrane

Predicted MW.

100 kDa

Observed MW.

140 kDa

Purity

Affinity purification

Subcellular location

Cell membrane,Cell junction,Cell surface

Uniprot ID

P19022, P15116, Q9Z1Y3



Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 1000-1: 2000

colon, brain,

cerebral cortex

IHC

Human, Mouse, Rat

1: 1000-1: 2000

colon

IF

Human, Mouse, Rat

1: 500-1: 1000

colon



Background


Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density.

 



Images



內(nèi)頁(yè).jpg

Western blot analysis of N Cadherin (GB12135) 

at dilution of 1: 1000

image.png



Immunohistochemistry analysis of paraffin-embedded human colon using 

N Cadherin (GB12135) at dilution of 1: 1500



image.png

Immunohistochemistry analysis of paraffin-embedded mouse colon using 

N Cadherin (GB12135) at dilution of 1: 1500

image.png

Immunohistochemistry analysis of paraffin-embedded rat colon using 

N Cadherin (GB12135) at dilution of 1: 1500




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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