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Product Information
Description |
NF-κB p65 mouse monoclonal |
Protein full name |
Transcription factor p65 |
Synonyms |
RELA, NFKB3, p65, RELA proto-oncogene, NF-kB subunit |
Immunogen |
KLH conjugated Synthetic peptide corresponding to human NF-κB p65 around the phosphorylation site of Serine 536 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
65 KDa |
Observed MW. |
65 KDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive cell |
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
Hela, HepG2, A549, MCF7, 293T, NIH/3T3, C2C12, Neuro-2a |
Background
Nuclear factor k B (NF-kB) is a sequence-specific DNA-binding protein complex which regulates the expression of viral genomes, including the human immunodeficiency virus, and a variety of cellular genes, particularly those involved in immune and inflammatory responses. The p65 subunit is a major component of NF-kB complexes and is responsible for trans-activation. NF-kB heterodimeric p65-p50 and p65-c-Rel complexes are transcriptional activators. The NF-kB p65-p65 complex appears to be involved in invasin-mediated activation of IL-8 expression.
Images
|
Western blot analysis of p65 (GB12142) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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