Anti -CDX2 Mouse mAb

價格：在線咨詢

貨號：

DRF101361

產品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產品詳情操作說明注意事項

Product Information

Description	CDX2 mouse monoclonal
Protein full name	Homeobox protein CDX-2
Synonyms	caudal type homeobox 2, Caudal type homeobox protein 2, CDX-3, CDX2, CDX-2, CDX3
Immunogen	Recombinant protein corresponding to Mouse CDX2
Isotype	IgG1
Purity	Affinity purification
Subcellular location	Nucleus
Uniprot ID	Q99626

Applications

Applications	Species	Dilution	Positive Tissue
IHC	Human	1: 1500-1: 3000	colon cancer, colon

Background

CDX2, also named as Homeobox protein CDX-2, is a 313 amino acid protein, which contains one homeobox DNA-binding domain and belongs to the Caudal homeobox family. CDX2 localizes in the nucleus and is involved in the transcriptional regulation of multiple genes expression in the intestinal epithelium. The relative expression of CDX1 to CDX2 protein may be important in the anterior to posterior patterning of the intestinal epithelium and in defining patterns of proliferation and differentiation along the crypt-villus axis. Both Cdx1 and Cdx2 genes must be expressed to reduce tumorigenic potential, to increase sensitivity to apoptosis, and to reduce cell migration, suggesting that the two genes control the normal phenotype by independent pathways.

Images

Immunohistochemistry analysis of paraffin-embedded human colon cancer using CDX2 (GB121500) at dilution of 1: 3000

Immunohistochemistry analysis of paraffin-embedded human colon using

CDX2 (GB121500) at dilution of 1: 3000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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