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Anti -PGP9.5 Mouse mAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101363
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

PGP9.5 mouse monoclonal

Protein full name

Ubiquitin carboxyl-terminal hydrolase isozyme L1

Synonyms

UCH-L1, Neuron cytoplasmic protein 9.5, PGP 9.5, PGP9.5, Ubiquitin thioesterase L1, Uchl1

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse PGP9.5

Isotype

IgG1

Purity

Affinity purification

Subcellular location

CytoplasmEndoplasmic reticulumMembrane

Predicted MW.

25 kDa

Observed MW.

25 kDa

Uniprot ID

P09936, Q9R0P9, Q00981




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 1000-1: 2000

brain, cortex, hippocampus

IHC

Human, Mouse, Rat

1: 1000-1: 2000

glioma, neuroendocrine tumor, stomach, colon, brain




Background


UCHL1(Ubiquitin carboxyl-terminal hydrolase isozyme L1) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons. This protein is present in brain at concentrations at least 50 times greater than in other organs and is a major protein component of neuronal cytoplasm . And UCHL1 is a Parkinson's disease susceptibility gene.




Images


Western blot analysis of PGP9.5 (GB12159) 

at dilution of 1: 2000

Lane 1: U87 cell lysate

Lane 2: N2A cell lysate

Lane 3: Human glioma cell lysate

Lane 4: Mouse brain tissue lysate

Lane 5: Mouse cortex tissue lysate

Lane 6: Mouse hippocampus tissue lysate

Lane 7: Rat brain tissue lysate

Lane 8: Rat cortex tissue lysate

Lane 9: Rat hippocampus tissue lysate

Immunohistochemistry analysis of paraffin-embedded human glioma using 

PGP9.5 (GB12159) at dilution of 1: 2000

Immunohistochemistry analysis of paraffin-embedded human neuroendocrine tumor using PGP9.5 (GB12159) at dilution of 1: 2000

Immunohistochemistry analysis of paraffin-embedded human stomach using 

PGP9.5 (GB12159) at dilution of 1: 2000

Immunohistochemistry analysis of paraffin-embedded mouse colon using 

PGP9.5 (GB12159) at dilution of 1: 2000

Immunohistochemistry analysis of paraffin-embedded rat colon using 

PGP9.5 (GB12159) at dilution of 1: 2000

Immunohistochemistry analysis of paraffin-embedded rat brain using 

PGP9.5 (GB12159) at dilution of 1: 2000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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