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Anti -ROCK2 Mouse mAb

價格: 在線咨詢
貨號:
DRF101364
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
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Product Information


Description

ROCK2 mouse monoclonal

Protein full name

Rho-associated protein kinase 2

Synonyms

Rho kinase 2, coiled-coil-containing protein kinase 2, ROCK-II, KIAA0619, Rho-associated, p164 ROCK 2, Rock2m, ROKalpha, Rho kinase 2

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse ROCK2

Isotype

IgG

Purity

Affinity purification

Predicted MW.

161 kDa

Observed MW.

180 kDa

Uniprot ID

O75116, P70336, Q62868




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

brain, liver, colon




Background


ROCK2 is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. It is an isozyme of ROCK1, is a target for the small GTPase Rho. ROCK2 is localized in both cytoplasm and nucleus, and the nucleus-localized ROCK2 can target p300 for phosphorylation to regulate its acetyltransferase activity.




Images


圖片 1.png Western blot analysis of ROCK2 (GB121692) 

at dilution of 1: 1000

Lane 1: HeLa cell lysate

Lane 2: MCF7 cell lysate

Lane 3: C2C12 cell lysate

Lane 4: Mouse brain tissue lysate

Lane 5: Mouse liver tissue lysate

Lane 6: Mouse colon tissue lysate

Lane 7: Rat liver tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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