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Product Information
Description |
ROCK2 mouse monoclonal |
Protein full name |
Rho-associated protein kinase 2 |
Synonyms |
Rho kinase 2, coiled-coil-containing protein kinase 2, ROCK-II, KIAA0619, Rho-associated, p164 ROCK 2, Rock2m, ROKalpha, Rho kinase 2 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse ROCK2 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
161 kDa |
Observed MW. |
180 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
brain, liver, colon |
Background
ROCK2 is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. It is an isozyme of ROCK1, is a target for the small GTPase Rho. ROCK2 is localized in both cytoplasm and nucleus, and the nucleus-localized ROCK2 can target p300 for phosphorylation to regulate its acetyltransferase activity.
Images
Western blot analysis of ROCK2 (GB121692)
at dilution of 1: 1000 Lane 1: HeLa cell lysate Lane 2: MCF7 cell lysate Lane 3: C2C12 cell lysate Lane 4: Mouse brain tissue lysate Lane 5: Mouse liver tissue lysate Lane 6: Mouse colon tissue lysate Lane 7: Rat liver tissue lysate |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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