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Product Information
Description |
Myelin Basic Protein mouse monoclonal |
Protein full name |
Myelin Basic Protein |
Synonyms |
MBP, entrez:4155, myelin basic protein |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Myelin Basic Protein |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
27 kDa |
Observed MW. |
17/20 kDa |
Subcellular location |
Myelin membrane, Cytoplasmic side of myelin |
Uniprot ID |
P04370, P02688 |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse,Rat |
1: 2000-1: 4000 |
brain, cerebral cortex, Hippocampus, spinal cord |
IHC |
Mouse, Rat |
1: 3000-1: 6000 |
brain |
IF |
Mouse, Rat |
1: 250-1: 500 |
brain |
Background
The classic group of MBP isoforms (isoform 4-isoform 13) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells.
Images
Western blot analysis of Myelin Basic Protein (GB12226) at dilution of 1: 3000 |
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Immunohistochemistry analysis of paraffin-embedded mouse brain using Myelin Basic Protein (GB12226) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat brain using Myelin Basic Protein (GB12226) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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