Anti -Hsp60 Mouse mAb

價格：在線咨詢

貨號：

DRF101385

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	HSP60 mouse monoclonal
Protein full name	60 kDa heat shock protein, mitochondrial
Synonyms	HSP60, HSP-60, HuCHA60, CPN60, 60 KDa Chaperonin, P60 Lymphocyte Protein, Heat Shock Protein 60
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse HSP60
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoplasm
Predicted MW.	60 kDa
Observed MW.	60 kDa
Uniprot ID	P10809, P63039, P63038

Applications

Applications	WB	IHC
Species	Human, Mouse, Rat	Human, Mouse, Rat
Dilution	1: 500-1: 1000	1: 1000-1: 2000
Positive tissue	Hela, HepG2, MCF7, NIH/3T3, PC12	colon, colon cancer, kidney

Background

Heat shock protein 60 (HSP60) is a mitochondrial chaperonin that is typically held responsible for the transportation and refolding of proteins from the cytoplasm into the mitochondrial matrix. In addition to its role as a heat shock protein, HSP60 functions as a chaperonin to assist in folding linear amino acid chains into their respective three-dimensional structure. Through the extensive study of groEL, HSP60’s bacterial homolog, HSP60 has been deemed essential in the synthesis and transportation of essential mitochondrial proteins from the cell's cytoplasm into the mitochondrial matrix. Further studies have linked HSP60 to diabetes, stress response, cancer and certain types of immunological disorders.

Images

	Western blot analysis of HSP60 (GB12243) at dilution of 1: 1000 Lane 1: Hela cell lysate Lane 2: HepG2 cell lysate Lane 3: MCF7 cell lysate Lane 4: NIH/3T3 cell lysate Lane 5: PC12 cell lysate
	Immunohistochemistry analysis of paraffin-embedded human colon using HSP60 (GB12243) at dilution of 1: 2000
	IImmunohistochemistry analysis of paraffin-embedded human colon cancer using HSP60 (GB12243) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded mouse kidney using HSP60 (GB12243) at dilution of 1: 2000
	Immunohistochemistry analysis of paraffin-embedded rat kidney using HSP60 (GB12243) at dilution of 1: 2000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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