Anti -BMP2 Mouse mAb

價(jià)格：在線咨詢

貨號：

DRF101388

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	BMP2 mouse monoclonal
Protein full name	Bone morphogenetic protein 2
Synonyms	BMP2, BDA2, BMP2A,bone morphogenetic protein 2
Immunogen	Recombinant protein corresponding to Mouse BMP2
Isotype	IgG
Purity	Affinity purification
Subcellular location	Secreted
Uniprot ID	P12643,P21274,P49001

Applications

Applications	IHC,IF
Species	Rat
Dilution	1:500-1:1000
Positive tissue	bone

Background

Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.

Images

	Immunohistochemistry analysis of paraffin-embedded rat bone using BMP2 (GB12252) at dilution of 1:1000
	Immunohistochemistry analysis of paraffin-embedded rat bone using BMP2 (GB12252) at dilution of 1:1000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.

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