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Product Information
Description |
EpCAM mouse monoclonal |
Protein full name |
Epithelial cell adhesion molecule |
Synonyms |
EPCAM, DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, M4S1, MIC18, MK-1, TACSTD1, TROP1, epithelial cell adhesion molecule |
Immunogen |
Recombinant protein corresponding to Mouse EpCAM |
Isotype |
IgG2a |
Purity |
Affinity purification |
Subcellular location |
|
Predicted MW. |
35 kDa |
Observed MW. |
35 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human |
1: 1000-1: 2000 |
MCF-7, HT29, A-431 |
IHC |
Human |
1: 2000-1: 4000 |
colon cancer |
Background
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
Images
|
Western blot analysis of EpCAM (GB12274) at dilution of 1: 1000 |
|
Immunohistochemistry analysis of paraffin-embedded human colon cancer using EpCAM (GB12274) at dilution of 1: 2000 |
|
Immunohistochemistry analysis of paraffin-embedded human colon using EpCAM (GB12274) at dilution of 1: 2000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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