Anti -Hsp90 Mouse mAb

價格：在線咨詢

貨號：

DRF101392

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	HSP90 mouse monoclonal
Protein full name	Heat shock protein HSP 90-alphav
Synonyms	HSP90AA1, EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP-2, LAP2, HEL-S-65p, Heat shock protein 90kDa alpha
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse HSP90A
Isotype	IgG
Subcellular location	Nucleus, Cell membrane, Cytoplasm
Predicted MW.	90 kDa
Observed MW.	90 kDa
Purity	Affinity purification
Uniprot ID	P07900, P82995, P07901

Applications

Applications	Species	Dilution	Positive Ttissue
WB	Human, Mouse, Rat	1: 500-1: 1000	brain, testis
IHC	Mouse, Rat	1: 500-1: 1000	testis, ovary, brain, colon
IF	Mouse, Rat	1: 500-1: 1000

Background

Complemented by the constitutively expressed paralog Hsp90B which shares over 85% amino acid sequence identity, Hsp90A expression is initiated when a cell experiences proteotoxic stress. Once expressed Hsp90A dimers operate as molecular chaperones that bind and fold other proteins into their functional 3-dimensional structures. This molecular chaperoning ability of Hsp90A is driven by a cycle of structural rearrangements fueled by ATP hydrolysis. Current research on Hsp90A focuses in its role as a drug target due to its interaction with a large number of tumor promoting proteins and its role in cellular stress adaptation.

Images

	Western blot analysis of HSP90 (GB12284) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded mouse testis using HSP90 (GB12284) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded rat testis using HSP90 (GB12284) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded mouse ovary using HSP90 (GB12284) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded rat ovary using HSP90 (GB12284) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded mouse brain using HSP90 (GB12284) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded rat brain using HSP90 (GB12284) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded rat colon using HSP90 (GB12284) at dilution of 1: 1000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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