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Anti -MEK1 Mouse mAb

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貨號(hào):
DRF101393
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
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Product Information


Description

MEK1 mouse monoclonal

Protein full name

Dual specificity mitogen-activated protein kinase kinase 1

Synonyms

MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1, mitogen activated protein kinase kinase 1, ERK activator kinase 1, MAP kinase kinase 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse MEK1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus, Membrane

Uniprot ID

Q02750, Q01986, P31938




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 1000-1: 2000

lung, kidney, brain




Background  


The protein is a member of the dual-specificity protein kinase family that acts as amitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon activation by a wide variety of extra- and intracellular signals. As an essential component of the MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.




Images



2.jpg

Western blot analysis of MEK1

(GB12304) at dilution of 1: 1000

Lane 1: HUVEC cell lysate

Lane 2: A549 cell lysate

Lane 3: HepG2 cell lysate

Lane 4: Mouse lung tissue lysate

Lane 5: Mouse kidney tissue lysate

Lane 6: Mouse brain tissue lysate

Lane 7: Rat lung tissue lysate

Lane 8: Rat kidney tissue lysate

Lane 9: Rat brain tissue lysate




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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