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Product Information
Description |
HDAC1 mouse monoclonal |
Protein full name |
Histone deacetylase 1 |
Synonyms |
HDAC1, GON-10, HD1, RPD3, RPD3L1, histone deacetylase 1 |
Immunogen |
Recombinant protein corresponding to Mouse HDAC1 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
|
Predicted MW. |
55 kDa |
Observed MW. |
62 kDa |
Uniprot ID |
Applications
applications |
species |
dilution |
Positive tissue |
WB |
Mouse, Rat |
1: 500-1: 1000 |
testis, thymus |
IHC |
Human, Mouse, Rat |
1: 1000-1: 2000 |
lung cancer, liver cancer, colon cancer, ovary cancer, heart, testis, brain, kidney |
IF |
Human, Mouse, Rat |
1: 1000-1: 2000 |
small intestine cancer, colon, brain, lung, testis, kidney, heart |
Background
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2 MTA2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Images
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Western blot analysis of HDAC1 (GB12333) at dilution of 1: 1000 Lane 1: NIH3T3 cell lysate Lane 2: Mouse testis tissue lysate Lane 3: Mouse thymus tissue lysate Lane 4: Rat testis tissue lysate |
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Immunohistochemistry analysis of paraffin-embedded human lung cancer using HDAC1 (GB12333) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded human liver cancer using HDAC1 (GB12333) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded human colon cancer using HDAC1 (GB12333) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded human ovary cancer using HDAC1 (GB12333) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse heart using HDAC1 (GB12333) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse testis using HDAC1 (GB12333) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat testis using HDAC1 (GB12333) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse brain using HDAC1 (GB12333) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat brain using HDAC1 (GB12333) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse kidney using HDAC1 (GB12333) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat kidney using HDAC1 (GB12333) at dilution of 1: 1000 |
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Immunofluorescent analysis of paraformaldehyde-fixed human small intestine using HDAC1 (GB12333) at dilution of 1: 1000 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat colon using HDAC1 (GB12333) at dilution of 1: 1000 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat brain using HDAC1 (GB12333) at dilution of 1: 1000 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat lung using HDAC1 (GB12333) at dilution of 1: 1000 |
|
Immunofluorescent analysis of paraformaldehyde-fixed rat testis using HDAC1 (GB12333) at dilution of 1: 1000 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat kidney using HDAC1 (GB12333) at dilution of 1: 1000 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat heart using HDAC1 (GB12333) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
合肥萬物生物科技有限公司
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