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Anti -S100 beta Mouse mAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101401
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

S100 beta mouse monoclonal

Protein full name

Protein S100-B

Synonyms

S100B, NEF, S100, S100-B, S100beta,

S100 calcium binding protein B, S100β

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse S100B

Isotype

IgG1

Purity

Affinity purification

Subcellular location

Nucleus, Cytoplasm

Uniprot ID

P50114, P04631




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 1000-1: 2000

brain




Background


S100B is glial-specific and is expressed primarily by astrocytes, but not 

all astrocytes express S100B. It has been shown that S100B is only 

expressed by a subtype of mature astrocytes that ensheath blood 

vessels and by NG2-expressing cells.This protein may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, 

inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. In the developing 

CNS, it acts as a neurotrophic factor and neuronal survival protein. 

In the adult organism. it is usually elevated due to nervous system 

damage, which makes it a potential clinical marker.




Images


Immunohistochemistry analysis of paraffin-embedded mouse brain using 

S100B (GB12359) at dilution of 1: 2000

Immunohistochemistry analysis of paraffin-embedded mouse brain using 

S100B (GB12359) at dilution of 1: 2000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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