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Product Information
Description | Caspase-12 Mouse Monoclonal? |
Protein full name | Caspase-12 |
Synonyms | Casp12, CASP-12, CASP12P1, Inactive caspase-12, caspase 12 pseudogene 1, caspase 12 (gene/pseudogene) |
Immunogen | Recombinant protein corresponding to Mouse Caspase-12 |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 48 kDa |
Observed MW. | 50 kDa |
Uniprot ID | O08736 |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Mouse | 1: 500-1: 1000 |
heart, lung, skeletal muscle |
Background
Caspase 12 is an enzyme known as a cysteine protease. It belongs to a family of enzymes called caspases that cleave their substrates at C-terminal aspartic acid residues. It is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. Caspase-12 is located in the endoplasmic reticulum (ER). It is responsible for ER-stress-induced apoptosis, such as high calcium concentration, low oxygen and low glucose levels.
Images
Western blot analysis of Caspase-12 (GB12548) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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