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Anti -Sarcomeric Alpha Actinin Mouse mAb
價(jià)格：
在線咨詢
貨號(hào)：
DRF101411
產(chǎn)品規(guī)格：
100 μL
Applications：
Species：
購買數(shù)量：
產(chǎn)品詳情
操作說明
注意事項(xiàng)
Product Information
|
Description |
Sarcomeric Alpha Actinin mouse monoclonal |
|
Protein full name |
Alpha-actinin-2 |
|
Synonyms |
ACTN2, CMD1AA, CMH23, Actinin alpha 2, alpha Actinin 2 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse alpha Actinin 2 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
|
|
Predicted MW. |
104 kDa |
|
Observed MW. |
104 kDa |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
heart, skeletal muscle |
|
IHC |
Human, Mouse, Rat |
1: 1500-1: 3000 |
heart, skeletal muscle |
| IF | Human, Mouse, Rat | 1: 2000-1: 4000 |
|
Background
The primary function of alpha-actinin 2 is to crosslink filamentous actin molecules and titin molecules from adjoining sarcomeres at Z-discs, a function that is modulated by phospholipids. It is clear from studies by Hampton etal. that this crosslinking can assume a variety of conformations, with preferences for 60° and 120° angles. Alpha-actinin 2 also functions in docking signaling molecules at Z-discs, and additional studies have also implicated alpha-actinin 2 in the binding of cardiac ion channels, Kv1.5 in particular.
Images
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|
Western blot analysis of alpha Actinin 2 (GB12555) at dilution of 1: 1000 Lane 1: Mouse heart tissue lysate Lane 2: Mouse skeletal muscle tissue lysate Lane 3: Rat heart tissue lysate Lane 4: Rat skeletal muscle tissue lysate |
|
|
Immunohistochemistry analysis of paraffin-embedded mouse heart using alpha Actinin 2 (GB12555) at dilution of 1: 2000 |
|
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Immunohistochemistry analysis of paraffin-embedded rat heart using alpha Actinin 2 (GB12555) at dilution of 1: 2000 |
|
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Immunohistochemistry analysis of paraffin-embedded rat skeletal muscle using alpha Actinin 2 (GB12555) at dilution of 1: 2000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國家大學(xué)科技園A401室