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Product Information
Description |
CCL3 mouse monoclonal |
Protein full name |
C-C motif chemokine 3 |
Synonyms |
Ccl3, CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3, C-C motif chemokine ligand 3, Macrophage Inflammatory Protein 1 alpha, Tonsillar lymphocyte LD78 alpha protein, MIP-1-alpha |
Immunogen |
Recombinant protein corresponding to Mouse CCL3 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Secreted |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Mouse |
1: 500-1: 1000 |
Pneumonia, septic liver, splenitis |
Background
CCL3 is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes through binding to the receptors CCR1, CCR4 and CCR5. CCL3 has been shown to interact with CCL4, and attracts macrophages, monocytes and neutrophils. CCL3 produces a monophasic fever of rapid onset whose magnitude is equal to or greater than that of fevers produced with either recombinant human tumor necrosis factor or recombinant human interleukin-1.
Images
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Immunohistochemistry analysis of paraffin-embedded mouse pneumonia using CCL3 (GB12687) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse septic liver using CCL3 (GB12687) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse splenitis using CCL3 (GB12687) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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