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Product Information
Description |
Bax mouse monoclonal |
Protein full name |
Apoptosis regulator BAX |
Synonyms |
BAX, BCL2L4, BCL2 associated X protein, BCL2 associated X, apoptosis regulator |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Bax |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
21 kDa |
Observed MW. |
18 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
liver, lung, kidney |
Background
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Images
|
Western blot analysis of Bax (GB12690) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
合肥萬物生物科技有限公司
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