Anti -P53 Mouse MAb

價格：在線咨詢

貨號：

DRF101435

產(chǎn)品規(guī)格：

50 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	P53 mouse monoclonal
Protein full name	TP53
Synonyms	BCC7, LFS1, TRP53
Immunogen	Recombinant human wild-type p53 protein.
Isotype	IgG
Purity	Ascites
Subcellular location	Cytoplasm, Nucleus
Uniprot ID	P04637

Applications

Applications	Species	Dilution	Positive Tissue
IHC	Human	1: 50-1: 400	mammary cancer

Background

The p53 tumor antigen is found in increased amounts in a wide variety of transformed cells. The protein is also detectable in many actively proliferating, nontransformed cells, but it is undetectable or present at low levels in resting cells. This protein induces cell cycle arrest or apoptosis in response to sublethal or severe DNA damage, respectively, by differential transcription of target genes and through transcription-independent apoptotic functions. The p53 protein contains 393 amino acids. Human p53 tumour antigen is Locatedto band 17p13. p53 mutations are common in pancreatic cancer and are absent in chronic pancreatitis.

Images

Storage

Storage	12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
Storage Buffer	Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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