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Anti -P27 Mouse mAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101445
產(chǎn)品規(guī)格:
50 μL
Applications:
Species:
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description P27 mouse monoclonal
Protein full name Cyclin-dependent kinase inhibitor 1B
Synonyms CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1, cyclin-dependent kinase inhibitor 1B, cyclin dependent kinase inhibitor 1B
Immunogen Recombinant full length protein (proprietary-tag) corresponding to Human p27 KIP 1 aa 1-198.
Isotype IgG
Purity Affinity purification
Subcellular location Nucleus, Cytoplasm
Uniprot ID P46527, P46414, O08769




Applications


Applications Species Dilution Positive Tissue
IHC Human, Mouse, Rat 1:100-1:1000 colon




Background

Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.




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Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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