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Anti -Fascin Mouse mAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101537
產(chǎn)品規(guī)格:
50 μL
Applications:
Species:
購買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Gene Name FSCN1 FAN1 HSN SNL
Protein Name Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55)
Human Gene Id 6624
Human Swiss Prot No Q16658
Immunogen Synthesized peptide derived from human Fascin
Specificity This antibody detects endogenous levels of human Fascin
Source Mouse/IgG1, Kappa
Concentration 1 mg/ml
Purification The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.




Applications


Applications Species Dilution
IHC、IF Human 1:200-1:500




Background

fascin actin-bundling protein 1(FSCN1) Homo sapiens This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011],




Images



Immunohistochemical analysis of paraffin-embedded Classical Hodgkin's lymphoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval.

Immunohistochemical analysis of paraffin-embedded Classical Hodgkin's lymphoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval.




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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