p300 HAT, E1A-associated protein p300, RSTS2, KAT3B, p300, CBP
Human Gene Id
5133
Human Swiss Prot No
Q09472
Immunogen
Recombinant fragment within Human KAT3B/ p300.
Specificity
This antibody detects endogenous levels of human KAT3B / p300
Source
Mouse/IgG1, Kappa
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Applications
Applications
Species
Dilution
IHC
Human
1:200-1:500
IF
Human
1:200-1:500
Background
EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.
Images
Immunohistochemical analysis of paraffin-embedded Tonsil. 1, Antibody was diluted at 1:200(4°,overnight). 2, Citric acid ,pH6.0 was used for antigen retrieval.
Immunohistochemical analysis of paraffin-embedded Tonsil. 1, Antibody was diluted at 1:200(4°,overnight). 2, Citric acid ,pH6.0 was used for antigen retrieval.
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .