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Anti -CREBBP + KAT3B / p300 Mouse mAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101578
產(chǎn)品規(guī)格:
50 μL
Applications:
Species:
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Gene Name

EP300

Protein Name

Histone acetyltransferase p300

Synonyms

p300 HAT, E1A-associated protein p300, RSTS2, KAT3B, p300, CBP

Human Gene Id

5133

Human Swiss Prot No

Q09472

Immunogen

Recombinant fragment within Human KAT3B/ p300.

Specificity

This antibody detects endogenous levels of human KAT3B / p300

Source

Mouse/IgG1, Kappa

Concentration

1 mg/ml

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.




Applications


Applications

Species

Dilution

IHC

Human

1:200-1:500

IF

Human

1:200-1:500




Background

EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.




Images



Immunohistochemical analysis of paraffin-embedded Tonsil. 1, Antibody was diluted at 1:200(4°,overnight). 2, Citric acid ,pH6.0 was used for antigen retrieval.

Immunohistochemical analysis of paraffin-embedded Tonsil. 1, Antibody was diluted at 1:200(4°,overnight). 2, Citric acid ,pH6.0 was used for antigen retrieval.




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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