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Product Information
Description |
Fas Ligand rabbit polyclonal |
Protein full name |
Tumor necrosis factor ligand superfamily member 6 |
Synonyms |
ALPS1A, APO 1, Apo 1 antigen, APT1, CD95, FAS, FAS1, FASLG receptor, FASTM, TNFRSF6 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse FASL |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
IHC | Human, Mouse, Rat | 1: 500-1: 3000 |
Appendix, spleen, Thymus, liver |
IF | Mouse, Rat |
1: 1500- 1: 3000 |
small intestine, thymus, lung |
Background
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
Images
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Immunohistochemistry analysis of paraffin-embedded human appendix using FasL (GB11090-1) at dilution of 1:1000 |
Immunohistochemistry analysis of paraffin-embedded mouse Immunized spleen using FasL (GB11090-1) at dilution of 1:1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse Immunized thymus using FasL (GB11090-1) at dilution of 1:1000 | |
Immunohistochemistry analysis of paraffin-embedded rat liver using FasL (GB11090-1) at dilution of 1:1000 |
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Immunohistochemistry analysis of paraffin-embedded rat spleen using FasL (GB11090-1) at dilution of 1:1000 |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse small intestine using FasL(GB11090-1) at dilution of 1: 1500 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat thymus using FasL(GB11090-1) at dilution of 1: 1500 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat lung using FasL(GB11090-1) at dilution of 1: 3000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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