Anti -CTLA4 Rabbit pAb

價格：在線咨詢

貨號：

DRF101626

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	CTLA4 rabbit polyclonal
Protein full name	Cytotoxic T-lymphocyte protein 4
Synonyms	Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4, CD152, CTLA4, ALPS5, CELIAC3, GRD4, GSE, ICOS, IDDM12
Immunogen	KLH conjugated Synthetic peptide corresponding to Human CTLA4
Isotype	IgG
Purity	Affinity purification
Predicted MW.	25 kDa
Observed MW.	25 kDa
Uniprot ID	P09793

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse, Rat	1: 500-1: 1000	spleen, lung

Background

CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function.

Images

圖片 1.png

Western blot analysis of CTLA4 (GB111877)

at dilution of 1: 1000

Lane 1: Mouse spleen tissue lysate

Lane 2: Mouse lung tissue lysate

Lane 3: Rat spleen tissue lysate

Lane 4: Rat lung tissue lysate

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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