Anti -Fas Mouse mAb

價格：在線咨詢

貨號：

DRF101637

產品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產品詳情操作說明注意事項

Product Information

Description	Fas mouse monoclonal
Protein full name	Tumor necrosis factor receptor superfamily member 6
Synonyms	FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6, Fas cell surface death receptor
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse FAS
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cell membrane,Secrete
Uniprot ID	P25445,P25446

Applications

Applications	IHC,IF
Species	Human,Mouse
Dilution	1:200-1:800
Positive tissue	Gallbadder,colon

Background

Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

Images

	Immunohistochemistry analysis of paraffin-embedded human gallbladder using FAS (GB12089) at dilution of 1:200
	Immunohistochemistry analysis of paraffin-embedded mouse colon using FAS (GB12089) at dilution of 1:400
	Immunohistochemistry analysis of paraffin-embedded mouse testis using FAS (GB12089) at dilution of 1:400

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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