Anti -Fas Rabbit pAb

價格：在線咨詢

貨號：

DRF101641

產(chǎn)品規(guī)格：

50 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	Fas rabbit polyclonal
Protein full name	Tumor necrosis factor receptor superfamily member 6
Synonyms	FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6, Fas cell surface death receptor
Immunogen	KLH conjugated Synthetic peptide corresponding to human FAS
Isotype	IgG
Purity	Affinity purification
Predicted MW.	38 kDa
Observed MW.	38 kDa
Uniprot ID	P25445, Q63199, P25446

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1:500-1:1000	kidney

Background

Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

Images

All lanes are rat kidney tissue lysate Western blot analysis of FAS (GB13089) at dilution of 1:1000.

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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