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Product Information
Description |
CCL3 rabbit polyclonal |
Protein full name |
C-C motif chemokine 3 |
Synonyms |
Heparin-binding chemotaxis protein, L2G25B, Macrophage inflammatory protein 1-alpha, MIP-1-alpha, SIS-alpha, Small-inducible cytokine A3, TY-5, Ccl3, Mip1a, Scya3 |
Immunogen |
Recombinant protein corresponding to Mouse CCL3 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
|
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Mouse, Rat |
1: 1000-1: 2000 |
sepsis lung, sepsis spleen, spleen |
Background
The MIP-1 alpha is a monokine with inflammatory, pyrogenic and chemokinetic properties. Has a potent chemotactic activity for eosinophils. Binding to a high-affinity receptor activates calcium release in neutrophils.MIP-1 proteins have been reported to have multiple effects on hematopoietic precursor cells and MIP-1 alpha has been identified as a stem cell inhibitory factor that can inhibit the proliferation of hematopoietic stem cells in vitro as well as in vivo. The functional receptor for MIP-1 alpha has been identified as CCR1 and CCR5.
Images
Immunohistochemistry analysis of paraffin-embedded mouse sepsis lung using CCL3 (GB111212) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat sepsis lung using CCL3 (GB111212) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse sepsis spleen using CCL3 (GB111212) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat sepsis spleen using CCL3 (GB111212) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse spleen using CCL3 (GB111212) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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