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Product Information
Description |
CX3CL1 rabbit polyclonal |
Protein full name |
Fractalkine |
Synonyms |
C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, Neurotactin, Small-inducible cytokine D1, Processed fractalkine, CX3CL1, FKN, NTT, SCYD1 |
Immunogen |
Recombinant protein corresponding to Human CX3CL1 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Cell membrane, Secreted |
Uniprot ID |
P78423 |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Human |
1: 2000-1: 4000 |
lung cancer, tonsil |
Background
CX3CL1 is a member of the delta chemokine subfamily that contains a unique CX3C cysteine motif near the N-terminal. Unlike other known chemokines, it is a type 1 membrane protein containing a chemokine domain tethered on a long mucin-like stalk. The CX3CL1 is a leukocyte chemoattractant and expressed in various tissues .The expression is reported to be up-regulated in endothelial cells and microglia by inflammatory signals. CX3CR1, a specific receptor for fractalkine, mediates both leukocyte migration and adhesion.
Images
|
Immunohistochemistry analysis of paraffin-embedded human lung cancer using CX3CL1 (GB111262) at dilution of 1: 2000 |
|
Immunohistochemistry analysis of paraffin-embedded human tonsil using CX3CL1 (GB111262) at dilution of 1: 2000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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