Anti -CCR3 Rabbit pAb

價格：在線咨詢

貨號：

DRF101716

產品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產品詳情操作說明注意事項

Product Information

Description	CCR3 rabbit polyclonal
Protein full name	Probable C-C chemokine receptor type 3
Synonyms	C-C CKR-3, CC-CKR-3, CCR-3, CCR3, CKR3, Macrophage inflammatory protein 1-alpha receptor-like 2, IP-1 alpha RL2, CD193, Ccr3, Cmkbr1l2, Cmkbr3
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse CCR3
Isotype	IgG
Purity	Affinity purification
Predicted MW.	42 kDa
Observed MW.	50 kDa
Uniprot ID	P51678

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse	1: 300-1: 600	liver

Background

The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3(CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21.

Images

Western blot analysis of CCR3 (GB112453)

at dilution of 1: 600

Lane 1: Mouse liver tissue lysate

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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