Anti -CX3CR1 Rabbit pAb

價格：在線咨詢

貨號：

DRF101730

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	CX3CR1 rabbit polyclonal
Protein full name	CX3C chemokine receptor 1
Synonyms	Cx3cr1, CX3CR1, CCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, V28, C-X3-C motif chemokine receptor 1
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse CX3CR1
Isotype	IgG
Purity	Affinity purification
Predicted MW.	40 kDa
Observed MW.	40 kDa
Uniprot ID	P49238, Q9Z0D9, P35411

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1: 500-1: 1000	spleen, lung, brain

Background

CX3C chemokine receptor 1 (CX3CR1) also known as the fractalkine receptor or G-protein coupled receptor 13 (GPR13) is a protein which binds the chemokine CX3CL1 (also called neurotactin or fractalkine). The fractalkine ligand CX3CL1 is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. Expression of this receptor appears to be associated with lymphocytes. CX3CR1 is also expressed by monocytes and plays a major role in the survival of monocytes. Fractalkine signaling has also recently been discovered to play a developmental role in the migration of microglia in the central nervous system to their synaptic targets, where phagocytosis and synaptic refinement occur.

Images

Western blot analysis of CX3CR1

(GB11711) at dilution of 1: 1000

Lane 1: HepG2 cell lysate

Lane 2: HCT116 cell lysate

Lane 3: CaCO2 cell lysate

Lane 4: Mouse spleen tissue lysate

Lane 5: Mouse lung tissue lysate

Lane 6: Mouse brain tissue lysate

Lane 7: Rat lung tissue lysate

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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