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Anti -CD31 Rabbit pAb

價格: 在線咨詢
貨號:
DRF101808
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

CD31 rabbit polyclonal

Protein full name

Platelet endothelial cell adhesion molecule

Synonyms

CD31 Antigen, EndoCAM, PECAM-1, GPIIA, PECA1

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse CD31 

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane

Predicted MW.

81 kDa

Observed MW.

120 kDa

Uniprot ID

P16284Q08481Q3SWT0



Applications


applications

species

dilution

Positive tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

lung, thymus

IHC

Human, Mouse, Rat

1: 600-1: 1200

liver cancer

IF

Human, Mouse, Rat

1: 200-1: 1000

gastric cancer, liver cancer, lung, placenta



Background


Platelet endothelial cell adhesion molecule (PECAM-1) also known as cluster of differentiation 31 (CD31) is a protein that in humans is encoded by the PECAM1 gene found on chromosome 17. PECAM-1 plays a key role in removing aged neutrophils from the body. PECAM-1 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte transmigration, angiogenesis, and integrin activation.




Images


圖片 1.png

Western blot analysis of CD31 (GB11063-2) 

at dilution of 1: 1000


圖片 7.png

Immunohistochemistry analysis of paraffin-embedded human liver cancer using CD31 (GB11063-2) at dilution of 1: 1000

圖片 5.png

Immunohistochemistry analysis of paraffin-embedded human liver cancer using CD31 (GB11063-2) at dilution of 1: 2000

圖片 19.png

Immunofluorescent analysis of paraformaldehyde-fixed human gastric cancer using CD31 (GB11063-2) at dilution of 1: 2000

圖片 20.png

Immunofluorescent analysis of paraformaldehyde-fixed human liver cancer using CD31 (GB11063-2) at dilution of 1: 2000

圖片 23.png

Immunofluorescent analysis of paraformaldehyde-fixed rat lung using 

CD31 (GB11063-2) at dilution of 1: 2000


圖片 24.png

Immunofluorescent analysis of paraformaldehyde-fixed rat placenta using 

CD31 (GB11063-2) at dilution of 1: 2000





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .



Publications:



Title

Journal

Pubmed ID

Application

1

IL-21 Stimulates the expression and activation of cell cycle regulators and promotes cell proliferation in EBV-positive diffuse large B cell lymphoma.

Scientific Reports

32704112

IHC

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