Anti -CD40 Rabbit pAb

價格：在線咨詢

貨號：

DRF101814

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	CD40 rabbit polyclonal
Protein full name	Tumor necrosis factor receptor superfamily member 5
Synonyms	B-cell surface antigen CD40, Bp50, CD40L receptor, CD40, Tnfrsf5, CDw40, GP39, HIGM1, IGM, IMD3, TBAM
Immunogen	Recombinant protein corresponding to Mouse CD40
Isotype	IgG
Purity	Affinity purification
Predicted MW.	32 kDa
Observed MW.	45 kDa
Uniprot ID	P27512, Q4QQW2

Applications

Applications

Species

Dilution

Positive Tissue

Mouse, Rat

1: 500-1: 1000

spleen, thymus,

lymph nodes

Background

CD40, also named as TNFRSF5 and Bp50, is a receptor for TNFSF5/CD40LG. It is a member of the TNFR super family and is responsible for the efficient activation of cell-mediated and humoral immune responses via activated T cells and B cells respectively. Defects in CD40 lead to hyper-IgM immunodeficiency syndrome type 3 (HIGM3) . This is an autosomal recessive disorder that includes the inability of B cells to undergo isotype switching, a key step in the final differentiation of the humoral immune response, and an inability to mount an antibody-specific immune response.

Images

Western blot analysis of CD40 (GB111033) at dilution of 1: 1000

Lane 1: A20 cell lysate

Lane 2: Mouse spleen tissue lysate

Lane 3: Mouse lymph nodes tissue lysate

Lane 4: Mouse thymus tissue lysate

Lane 5: Rat lymph nodes tissue lysate

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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