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Product Information
Description |
CD27 rabbit polyclonal |
Protein full name |
CD27 antigen |
Synonyms |
CD27, S152, S152. LPFS2, T14, TNFRSF7, Tp55, CD27 molecule |
Immunogen |
Recombinant protein corresponding to Mouse CD27 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
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Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Mouse, Rat |
1: 1000-1: 2000 |
lymphoid, spleen, thymus |
Background
CD27 (also known as TNFRSF7) is a type I glycoprotein expressed on some B cells and the majority of T cells, and is a member of the tumor necrosis factor (TNF) receptor family. CD27 is required for generation and long-term maintenance of T cell immunity. It is a receptor for CD70 (Cd27L). Ligation of CD27 by CD70 induces strong ubiquitination of TRAF and the activation of both canonical and non-canonical NF-kappaB pathways, as well as the JNK pathway. CD27 may also play a role in apoptosis through association with SIVA1.
Images
Immunohistochemistry analysis of paraffin-embedded mouse lymphoid using CD27 (GB111165) at dilution of 1: 2000 |
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Immunohistochemistry analysis of paraffin-embedded rat lymphoid using CD27 (GB111165) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD27 (GB111165) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat spleen using CD27 (GB111165) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse thymus using CD27 (GB111165) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.
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