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Product Information
Description |
CD276 rabbit polyclonal |
Protein full name |
CD276 antigen |
Synonyms |
B7 homolog 3, B7-H3, Costimulatory molecule, CD276, B7h3, 4Ig B7 H3 |
Immunogen |
Recombinant protein corresponding to Mouse CD276 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
34 kDa |
Observed MW. |
100 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human |
1: 500-1: 1000 |
HeLa, HepG2, A431, MCF7, 293T, U251, Jurkat, U2OS, Raji |
Background
B7-H3 (CD276) is a type I transmembrane protein expressed on many tissues and cell types. B7-H3 is a 100-kDa glycoprotein that belongs to the B7 immunoregulatory family and participates in the regulation of T-cell-mediated immune response probably by functioning as both a T cell costimulator and coinhibitor Overexpressed on a wide range of human solid cancers, B7-H3 has been implicated in cancer progression and metastasis and becomes an attractive target for cancer immunotherapy.
Images
|
Western blot analysis of CD276 (GB111975) at dilution of 1: 1000 Lane 1: HeLa cell lysate Lane 2: HepG2 cell lysate Lane 3: A431 cell lysate Lane 4: MCF7 cell lysate Lane 5: 293T cell lysate Lane 6: U251 cell lysate Lane 7: Jurkat cell lysate Lane 8: U2OS cell lysate Lane 9: Raji cell lysate |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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