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Anti -CD276 Rabbit pAb

價格: 在線咨詢
貨號:
DRF101831
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

CD276 rabbit polyclonal

Protein full name

CD276 antigen

Synonyms

B7 homolog 3, B7-H3, Costimulatory molecule, CD276, B7h3, 4Ig B7 H3

Immunogen

Recombinant protein corresponding to

Mouse CD276

Isotype

IgG

Purity

Affinity purification

Predicted MW.

34 kDa

Observed MW.

100 kDa

Uniprot ID

Q5ZPR3




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human

1: 500-1: 1000

HeLa, HepG2, A431, MCF7, 293T, U251, Jurkat, U2OS, Raji




Background


B7-H3 (CD276) is a type I transmembrane protein expressed on many tissues and cell types. B7-H3 is a 100-kDa glycoprotein that belongs to the B7 immunoregulatory family and participates in the regulation of T-cell-mediated immune response probably by functioning as both a T cell costimulator and coinhibitor  Overexpressed on a wide range of human solid cancers, B7-H3 has been implicated in cancer progression and metastasis and becomes an attractive target for cancer immunotherapy.




Images


圖片 1.png

Western blot analysis of CD276 (GB111975)

at dilution of 1: 1000

Lane 1: HeLa cell lysate

Lane 2: HepG2 cell lysate

Lane 3: A431 cell lysate

Lane 4: MCF7 cell lysate

Lane 5: 293T cell lysate

Lane 6: U251 cell lysate

Lane 7: Jurkat cell lysate

Lane 8: U2OS cell lysate

Lane 9: Raji cell lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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