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Anti -CD42b Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101832
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

CD42b rabbit polyclonal

Protein full name

Platelet glycoprotein Ib alpha chain

Synonyms

GP-Ib alpha, GPIb-alpha, GPIbA, Glycoprotein Ibalpha,  CD42b, BDPLT3, GLYCOCALICIN, VWDP, DBPLT3, CD42b-alpha

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse CD42b

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane

Uniprot ID

O35930




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Rat

1: 500-1: 1800

lung, spleen




Background


Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease.




Images


Immunohistochemistry analysis of paraffin-embedded rat lung using

CD42b (GB112044) at dilution of 1: 1800

Immunohistochemistry analysis of paraffin-embedded rat spleen using

CD42b (GB112044) at dilution of 1: 1800




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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