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Product Information
Description |
CD44 rabbit polyclonal |
Protein full name |
CD44 antigen |
Synonyms |
Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Hermes antigen, Hyaluronate receptor, Ly-24, CD44, PGP-I |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse CD44 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
|
Predicted MW. |
86 kDa |
Observed MW. |
95 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Mouse, Rat |
1: 100-1: 300 |
liver |
IHC |
Mouse, Rat |
1: 300-1: 600 |
liver, small intestine, spleen, lung, colon |
Background
CD44 is the receptor for hyaluronic acid (HA). It mediates cell to cell and cell matrix interactions through its affinity for HA. Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. High protein heterogeneity due to several alternative splicing and post translational modification events. CD44R represents a heterogeneous group of CD44 variant isoforms expressed constitutively in epithelial cells and monocyte lineage cells and can be upregulated in activated leukocytes.
Images
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Western blot analysis of CD44 (GB112054) at dilution of 1: 300 Lane 1: NIH3T3 cell lysate Lane 2: Mouse liver tissue lysate |
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Immunohistochemistry analysis of paraffin-embedded mouse liver using CD44 (GB112054) at dilution of 1: 600 |
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Immunohistochemistry analysis of paraffin-embedded mouse small intestine using CD44 (GB112054) at dilution of 1: 600 |
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Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD44 (GB112054) at dilution of 1: 600 |
|
Immunohistochemistry analysis of paraffin-embedded rat spleen using CD44 (GB112054) at dilution of 1: 600 |
|
Immunohistochemistry analysis of paraffin-embedded mouse lung using CD44 (GB112054) at dilution of 1: 600 |
|
Immunohistochemistry analysis of paraffin-embedded rat lung using CD44 (GB112054) at dilution of 1: 600 |
|
Immunohistochemistry analysis of paraffin-embedded rat colon using CD44 (GB112054) at dilution of 1: 600 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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