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Anti -CD44 Rabbit pAb

價格: 在線咨詢
貨號:
DRF101833
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

CD44 rabbit polyclonal

Protein full name

CD44 antigen

Synonyms

Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Hermes antigen, Hyaluronate receptor, Ly-24, CD44, PGP-I

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse CD44

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane

Predicted MW.

86 kDa

Observed MW.

95 kDa

Uniprot ID

P15379, P26051




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 100-1: 300

liver

IHC

Mouse, Rat

1: 300-1: 600

liver, small intestine, spleen, lung, colon




Background


CD44 is the receptor for hyaluronic acid (HA). It mediates cell to cell and cell matrix interactions through its affinity for HA. Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. High protein heterogeneity due to several alternative splicing and post translational modification events. CD44R represents a heterogeneous group of CD44 variant isoforms expressed constitutively in epithelial cells and monocyte lineage cells and can be upregulated in activated leukocytes.




Images


Western blot analysis of CD44 (GB112054)

at dilution of 1: 300

Lane 1: NIH3T3 cell lysate

Lane 2: Mouse liver tissue lysate

Immunohistochemistry analysis of paraffin-embedded mouse liver using

CD44 (GB112054) at dilution of 1: 600

Immunohistochemistry analysis of paraffin-embedded mouse small intestine using 

CD44 (GB112054) at dilution of 1: 600

Immunohistochemistry analysis of paraffin-embedded mouse spleen using

CD44 (GB112054) at dilution of 1: 600

Immunohistochemistry analysis of paraffin-embedded rat spleen using

CD44 (GB112054) at dilution of 1: 600

Immunohistochemistry analysis of paraffin-embedded mouse lung using

CD44 (GB112054) at dilution of 1: 600

Immunohistochemistry analysis of paraffin-embedded rat lung using

CD44 (GB112054) at dilution of 1: 600

Immunohistochemistry analysis of paraffin-embedded rat colon using

CD44 (GB112054) at dilution of 1: 600




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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